GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs9815354 | 1 | rs73081364 | chr3:41913616 | ULK4 | chr3:41288091-42003660:- | 0.64 | 9.5 | 2.29E-19 | Diastolic blood pressure |
| BLCA | cis | rs7224737 | 1 | rs731152 | chr17:40279680 | DHX58 | chr17:40253422-40264751:- | -0.25 | -4.56 | 6.82E-6 | Fibrinogen levels |
| BLCA | cis | rs7789940 | 1 | rs73140069 | chr7:75986790 | UPK3B | chr7:76139745-76157197:+ | -0.3 | -6.33 | 6.76E-10 | Multiple sclerosis |
| BLCA | cis | rs2243480 | 1 | rs73142121 | chr7:65311206 | CCT6P1 | chr7:65216092-65228661:+ | 0.32 | 4.48 | 1.0E-5 | Diabetic kidney disease |
| BLCA | cis | rs2243480 | 1 | rs73142122 | chr7:65311298 | CCT6P1 | chr7:65216092-65228661:+ | 0.33 | 4.46 | 1.08E-5 | Diabetic kidney disease |
| BLCA | cis | rs2243480 | 1 | rs73142162 | chr7:65374296 | CCT6P1 | chr7:65216092-65228661:+ | 0.33 | 4.45 | 1.11E-5 | Diabetic kidney disease |
| BLCA | cis | rs2243480 | 1 | rs73142166 | chr7:65375832 | CCT6P1 | chr7:65216092-65228661:+ | 0.33 | 4.46 | 1.07E-5 | Diabetic kidney disease |
| BLCA | cis | rs2243480 | 1 | rs73150014 | chr7:65450919 | CCT6P1 | chr7:65216092-65228661:+ | 0.32 | 4.36 | 1.7E-5 | Diabetic kidney disease |
| BLCA | cis | rs7324557 | 1 | rs7324557 | chr13:24296862 | PCOTH | chr13:24463028-24466241:+ | 0.38 | 5.95 | 6.11E-9 | Visceral adipose tissue adjusted for BMI |
| BLCA | cis | rs732528 | 1 | rs732528 | chr18:48378234 | MRO | chr18:48321491-48351754:- | 0.25 | 4.39 | 1.5E-5 | Entorhinal cortical thickness |
| BLCA | cis | rs7327064 | 1 | rs7327064 | chr13:36771017 | SOHLH2 | chr13:36742347-36871992:- | 0.4 | 5.12 | 4.77E-7 | Economic and political preferences |
| BLCA | cis | rs7714584 | 1 | rs73282234 | chr5:150195924 | LOC134466 | chr5:150310000-150326146:- | 0.59 | 6.99 | 1.23E-11 | Crohn's disease |
| BLCA | cis | rs7714584 | 1 | rs73282255 | chr5:150223647 | LOC134466 | chr5:150310000-150326146:- | 0.45 | 5.61 | 3.98E-8 | Crohn's disease |
| BLCA | cis | rs7714584 | 1 | rs73284126 | chr5:150261307 | LOC134466 | chr5:150310000-150326146:- | 0.47 | 6.2 | 1.42E-9 | Crohn's disease |
| BLCA | cis | rs7714584 | 1 | rs73284141 | chr5:150266086 | LOC134466 | chr5:150310000-150326146:- | 0.47 | 6.24 | 1.17E-9 | Crohn's disease |